Toxicology

We offer in vivo services in all common laboratory species. Flexible, fast, and responsive, our team and services are designed to support discovery and investigative toxicology. We routinely develop custom protocols to meet the challenges of client programs, but we also have a portfolio of routine protocols for client utilization.

Standard protocols are in place to support:

  • Acute tolerability
  • Repeat dose studies
  • Mechanistic investigation of target organ effects
  • Correlate toxicity findings to systemic exposure (TK)
  • Dose-ranging guidance for longer studies
  • Complete necropsy, histopathology and DMPK support
  • Novel protocol development to derisk and investigate drug candidate toxicity

Species supported:

  • Mouse
  • Rat
  • Rabbit
  • Dog
  • Pig
  • Non Human Primate

Routes of administration

  • Oral
  • Intravenous
  • Subcutaneous
  • Dermal
  • Buccal/sublingual
  • Custom route development

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